Florin Lab IKN-UKD

Publications

Key Publications

The brain's resting-state activity is shaped by synchronized cross-frequency coupling of neural oscillations
The brain's resting-state activity is shaped by synchronized cross-frequency coupling of neural oscillations
Esther Florin, Sylvain Baillet
NeuroImage  ·  01 May 2015  ·  doi:10.1016/j.neuroimage.2015.01.054
The effect of filtering on Granger causality based multivariate causality measures
The effect of filtering on Granger causality based multivariate causality measures
Esther Florin, Joachim Gross, Johannes Pfeifer, Gereon R. Fink, Lars Timmermann
NeuroImage  ·  01 Apr 2010  ·  doi:10.1016/j.neuroimage.2009.12.050
Does increased gamma activity in patients suffering from Parkinson’s disease counteract the movement inhibiting beta activity?
Does increased gamma activity in patients suffering from Parkinson’s disease counteract the movement inhibiting beta activity?
E. Florin, R. Erasmi, C. Reck, M. Maarouf, A. Schnitzler, G.R. Fink, L. Timmermann
Neuroscience  ·  01 May 2013  ·  doi:10.1016/j.neuroscience.2013.01.051
DBS-evoked cortical responses index optimal contact orientations and motor outcomes in Parkinson’s disease
DBS-evoked cortical responses index optimal contact orientations and motor outcomes in Parkinson’s disease
Rachel K. Spooner, Bahne H. Bahners, Alfons Schnitzler, Esther Florin
npj Parkinson's Disease  ·  11 Mar 2023  ·  doi:10.1038/s41531-023-00474-4

All

2024

Evoked response signatures explain deep brain stimulation outcomes
Bahne H. Bahners, Lukas L. Goede, Garance M. Meyer, Luise Poser, Lauren A. Hart, …, Alfons Schnitzler, Esther Florin, Andrea A. Kühn, Michael D. Fox, Andreas Horn
Cold Spring Harbor Laboratory  ·  06 Oct 2024  ·  doi:10.1101/2024.10.04.24314308
Impact of data processing varieties on DCM estimates of effective connectivity from task‐fMRI
Shufei Zhang, Kyesam Jung, Robert Langner, Esther Florin, Simon B. Eickhoff, Oleksandr V. Popovych
Human Brain Mapping  ·  01 Jun 2024  ·  doi:10.1002/hbm.26751
Modulation of DBS-induced cortical responses and movement by the directionality and magnitude of current administered
Rachel K. Spooner, Baccara J. Hizli, Bahne H. Bahners, Alfons Schnitzler, Esther Florin
npj Parkinson's Disease  ·  08 Mar 2024  ·  doi:10.1038/s41531-024-00663-9
Time-resolved quantification of fine hand movements as a proxy for evaluating bradykinesia-induced motor dysfunction
Rachel K. Spooner, Bahne H. Bahners, Alfons Schnitzler, Esther Florin
Scientific Reports  ·  04 Mar 2024  ·  doi:10.1038/s41598-024-55862-4
Data‐driven MEG analysis to extract fMRI resting‐state networks
Esther A. Pelzer, Abhinav Sharma, Esther Florin
Human Brain Mapping  ·  01 Mar 2024  ·  doi:10.1002/hbm.26644
Deep brain stimulation device-specific artefacts in MEG recordings
Bahne H. Bahners, Roxanne Lofredi, Tilmann Sander, Alfons Schnitzler, Andrea A. Kühn, Esther Florin
Brain Stimulation  ·  01 Jan 2024  ·  doi:10.1016/j.brs.2024.01.005

2023

Resting State Network alterations during Deep Brain Stimulation in Parkinson’s Disease
Ahmet Levent Kandemir, Alfons Schnitzler, Esther Florin
Cold Spring Harbor Laboratory  ·  09 Nov 2023  ·  doi:10.1101/2023.11.08.23298114
Combining magnetoencephalography with telemetric streaming of intracranial recordings and deep brain stimulation—A feasibility study
Mansoureh Fahimi Hnazaee, Matthias Sure, George C. O’Neill, Gaetano Leogrande, Alfons Schnitzler, Esther Florin, Vladimir Litvak
Imaging Neuroscience  ·  01 Nov 2023  ·  doi:10.1162/imag_a_00029
Spontaneous network transitions predict somatosensory perception
Abhinav Sharma, Joachim Lange, Diego Vidaurre, Esther Florin
Cold Spring Harbor Laboratory  ·  23 Oct 2023  ·  doi:10.1101/2023.10.19.563130
Local Field Potentials Predict Motor Performance in Deep Brain Stimulation for Parkinson's Disease
Johannes L. Busch, Jonathan Kaplan, Bahne H. Bahners, Jan Roediger, Katharina Faust, Gerd‐Helge Schneider, Esther Florin, Alfons Schnitzler, Patricia Krause, Andrea A. Kühn
Movement Disorders  ·  12 Oct 2023  ·  doi:10.1002/mds.29626
Alterations of PAC-based resting state networks in Parkinson’s disease are partially alleviated by levodopa medication
Sean Mertiens, Matthias Sure, Alfons Schnitzler, Esther Florin
Frontiers in Systems Neuroscience  ·  01 Aug 2023  ·  doi:10.3389/fnsys.2023.1219334
A First Methodological Development and Validation of ReTap: An Open-Source UPDRS Finger Tapping Assessment Tool Based on Accelerometer-Data
Jeroen G. V. Habets, Rachel K. Spooner, Varvara Mathiopoulou, Lucia K. Feldmann, Johannes L. Busch, Jan Roediger, Bahne H. Bahners, Alfons Schnitzler, Esther Florin, Andrea A. Kühn
Sensors  ·  31 May 2023  ·  doi:10.3390/s23115238
Slowing of Frontal β Oscillations in Atypical Parkinsonism
Marius Krösche, Silja Kannenberg, Markus Butz, Christian J. Hartmann, Esther Florin, Alfons Schnitzler, Jan Hirschmann
Movement Disorders  ·  01 May 2023  ·  doi:10.1002/mds.29378
DBS-evoked cortical responses index optimal contact orientations and motor outcomes in Parkinson’s disease
Rachel K. Spooner, Bahne H. Bahners, Alfons Schnitzler, Esther Florin
npj Parkinson's Disease  ·  11 Mar 2023  ·  doi:10.1038/s41531-023-00474-4
Subthalamic stimulation evoked cortical responses relate to motor performance in Parkinson's disease
Bahne H. Bahners, Rachel K. Spooner, Christian J. Hartmann, Alfons Schnitzler, Esther Florin
Brain Stimulation  ·  01 Mar 2023  ·  doi:10.1016/j.brs.2023.02.014
Alterations of resting-state networks of Parkinson‘s disease patients after subthalamic DBS surgery
Matthias Sure, Sean Mertiens, Jan Vesper, Alfons Schnitzler, Esther Florin
NeuroImage: Clinical  ·  01 Jan 2023  ·  doi:10.1016/j.nicl.2023.103317

2022

Whole-brain dynamical modelling for classification of Parkinson’s disease
Kyesam Jung, Esther Florin, Kaustubh R Patil, Julian Caspers, Christian Rubbert, Simon B Eickhoff, Oleksandr V Popovych
Brain Communications  ·  15 Dec 2022  ·  doi:10.1093/braincomms/fcac331
Cortical network formation based on subthalamic beta bursts in Parkinson's disease
Matthias Sure, Jan Vesper, Alfons Schnitzler, Esther Florin
NeuroImage  ·  01 Nov 2022  ·  doi:10.1016/j.neuroimage.2022.119619
Electrophysiological characterization of the hyperdirect pathway and its functional relevance for subthalamic deep brain stimulation
Bahne Hendrik Bahners, Gunnar Waterstraat, Silja Kannenberg, Gabriel Curio, Alfons Schnitzler, Vadim Nikulin, Esther Florin
Experimental Neurology  ·  01 Jun 2022  ·  doi:10.1016/j.expneurol.2022.114031
Neuronal oscillations predict deep brain stimulation outcome in Parkinson's disease
Jan Hirschmann, Alexandra Steina, Jan Vesper, Esther Florin, Alfons Schnitzler
Brain Stimulation  ·  01 May 2022  ·  doi:10.1016/j.brs.2022.05.008
Toward therapeutic electrophysiology: beta-band suppression as a biomarker in chronic local field potential recordings
Lucia K. Feldmann, Roxanne Lofredi, Wolf-Julian Neumann, Bassam Al-Fatly, Jan Roediger, …, Katharina Faust, Esther Florin, Alfons Schnitzler, Gerd-Helge Schneider, Andrea A. Kühn
npj Parkinson's Disease  ·  19 Apr 2022  ·  doi:10.1038/s41531-022-00301-2
Separating Neural Oscillations from Aperiodic 1/f Activity: Challenges and Recommendations
Moritz Gerster, Gunnar Waterstraat, Vladimir Litvak, Klaus Lehnertz, Alfons Schnitzler, Esther Florin, Gabriel Curio, Vadim Nikulin
Neuroinformatics  ·  07 Apr 2022  ·  doi:10.1007/s12021-022-09581-8
Cross-Frequency Brain Network Dynamics Support Pitch Change Detection
Soheila Samiee, Dominique Vuvan, Esther Florin, Philippe Albouy, Isabelle Peretz, Sylvain Baillet
The Journal of Neuroscience  ·  29 Mar 2022  ·  doi:10.1523/jneurosci.0630-21.2022
No Higher Risk-Seeking Tendencies or Altered Self-Estimation in a Social Decision-Making Task in Patients with Parkinson’s Disease
Alexandra C. Zapf, Ann-Kristin Folkerts, Larissa Kahler, Alfons Schnitzler, Paul Reker, Michael T. Barbe, Esther Florin, Elke Kalbe
Journal of Parkinson’s Disease  ·  14 Feb 2022  ·  doi:10.3233/jpd-212960

2021

Dopaminergic Modulation of Spectral and Spatial Characteristics of Parkinsonian Subthalamic Nucleus Beta Bursts
Matthias Sure, Jan Vesper, Alfons Schnitzler, Esther Florin
Frontiers in Neuroscience  ·  11 Nov 2021  ·  doi:10.3389/fnins.2021.724334
Separating neural oscillations from aperiodic 1/f activity: challenges and recommendations
Moritz Gerster, Gunnar Waterstraat, Vladimir Litvak, Klaus Lehnertz, Alfons Schnitzler, Esther Florin, Gabriel Curio, Vadim Nikulin
Cold Spring Harbor Laboratory  ·  16 Oct 2021  ·  doi:10.1101/2021.10.15.464483
Differential dopaminergic modulation of spontaneous cortico–subthalamic activity in Parkinson’s disease
Abhinav Sharma, Diego Vidaurre, Jan Vesper, Alfons Schnitzler, Esther Florin
eLife  ·  04 Jun 2021  ·  doi:10.7554/eLife.66057
Conflict processing networks: A directional analysis of stimulus-response compatibilities using MEG
Jessica Rosenberg, Qunxi Dong, Esther Florin, Praveen Sripad, Frank Boers, Martina Reske, N. Jon Shah, Jürgen Dammers
PLOS ONE  ·  25 Feb 2021  ·  doi:10.1371/journal.pone.0247408
EEG and MEG primers for tracking DBS network effects
Vladimir Litvak, Esther Florin, Gertrúd Tamás, Sergiu Groppa, Muthuraman Muthuraman
NeuroImage  ·  01 Jan 2021  ·  doi:10.1016/j.neuroimage.2020.117447

2020

The comparative performance of DBS artefact rejection methods for MEG recordings
Ahmet Levent Kandemir, Vladimir Litvak, Esther Florin
NeuroImage  ·  01 Oct 2020  ·  doi:10.1016/j.neuroimage.2020.117057
Recovery of Impaired Endogenous Pain Modulation by Dopaminergic Medication in Parkinson's Disease
Esther Florin, Kim C. Koschmieder, Alfons Schnitzler, Susanne Becker
Movement Disorders  ·  18 Sep 2020  ·  doi:10.1002/mds.28241
Deep Brain Stimulation Does Not Modulate Auditory-Motor Integration of Speech in Parkinson's Disease
Bahne H. Bahners, Esther Florin, Julian Rohrhuber, Holger Krause, Jan Hirschmann, Ruben van de Vijver, Alfons Schnitzler, Markus Butz
Frontiers in Neurology  ·  10 Jul 2020  ·  doi:10.3389/fneur.2020.00655
Characterization of information processing in the subthalamic area of Parkinson’s patients
Immo Weber, Esther Florin, Michael von Papen, Veerle Visser-Vandewalle, Lars Timmermann
NeuroImage  ·  01 Apr 2020  ·  doi:10.1016/j.neuroimage.2020.116518
Spontaneous network activity <35 ​Hz accounts for variability in stimulus-induced gamma responses
Jan Hirschmann, Sylvain Baillet, Mark Woolrich, Alfons Schnitzler, Diego Vidaurre, Esther Florin
NeuroImage  ·  01 Feb 2020  ·  doi:10.1016/j.neuroimage.2019.116374
Electrophysiological resting state networks of predominantly akinetic-rigid Parkinson patients: Effects of dopamine therapy
Lukas Schneider, Valentin Seeger, Lars Timmermann, Esther Florin
NeuroImage: Clinical  ·  01 Jan 2020  ·  doi:10.1016/j.nicl.2019.102147

2019

Quantitative Susceptibility Mapping and Resting State Network Analyses in Parkinsonian Phenotypes—A Systematic Review of the Literature
Esther A. Pelzer, Esther Florin, Alfons Schnitzler
Frontiers in Neural Circuits  ·  06 Aug 2019  ·  doi:10.3389/fncir.2019.00050

2018

Commentary: Evaluation of Phase-Amplitude Coupling in Resting State Magnetoencephalographic Signals: Effect of Surrogates and Evaluation Approach
Esther Florin, Sylvain Baillet
Frontiers in Computational Neuroscience  ·  16 Apr 2018  ·  doi:10.3389/fncom.2018.00026
Imaging of neural oscillations with embedded inferential and group prevalence statistics
Peter W. Donhauser, Esther Florin, Sylvain Baillet
PLOS Computational Biology  ·  06 Feb 2018  ·  doi:10.1371/journal.pcbi.1005990

2017

The influence of filtering and downsampling on the estimation of transfer entropy
Immo Weber, Esther Florin, Michael von Papen, Lars Timmermann
PLOS ONE  ·  17 Nov 2017  ·  doi:10.1371/journal.pone.0188210
Phase-coherence classification: A new wavelet-based method to separate local field potentials into local (in)coherent and volume-conducted components
M. von Papen, H.S. Dafsari, E. Florin, F. Gerick, L. Timmermann, J. Saur
Journal of Neuroscience Methods  ·  01 Nov 2017  ·  doi:10.1016/j.jneumeth.2017.08.021
Pre-target neural oscillations predict variability in the detection of small pitch changes
Esther Florin, Dominique Vuvan, Isabelle Peretz, Sylvain Baillet
PLOS ONE  ·  18 May 2017  ·  doi:10.1371/journal.pone.0177836

2016

Parkinson subtype-specific Granger-causal coupling and coherence frequency in the subthalamic area
Esther Florin, Johannes Pfeifer, Veerle Visser-Vandewalle, Alfons Schnitzler, Lars Timmermann
Neuroscience  ·  01 Sep 2016  ·  doi:10.1016/j.neuroscience.2016.06.052

2015

The role of sub-second neural events in spontaneous brain activity
Esther Florin, Masataka Watanabe, Nikos K Logothetis
Current Opinion in Neurobiology  ·  01 Jun 2015  ·  doi:10.1016/j.conb.2014.10.006
The brain's resting-state activity is shaped by synchronized cross-frequency coupling of neural oscillations
Esther Florin, Sylvain Baillet
NeuroImage  ·  01 May 2015  ·  doi:10.1016/j.neuroimage.2015.01.054

2014

Levodopa reinstates connectivity from prefrontal to premotor cortex during externally paced movement in Parkinson's disease
Damian M. Herz, Hartwig R. Siebner, Oliver J. Hulme, Esther Florin, Mark S. Christensen, Lars Timmermann
NeuroImage  ·  01 Apr 2014  ·  doi:10.1016/j.neuroimage.2013.11.023
Targeted reinforcement of neural oscillatory activity with real-time neuroimaging feedback
Esther Florin, Elizabeth Bock, Sylvain Baillet
NeuroImage  ·  01 Mar 2014  ·  doi:10.1016/j.neuroimage.2013.10.028

2013

Gait and upper limb variability in Parkinson’s disease patients with and without freezing of gait
Michael T. Barbe, Martin Amarell, Anke H. Snijders, Esther Florin, Eva-Lotte Quatuor, Eckhard Schönau, Gereon R. Fink, Bastiaan R. Bloem, Lars Timmermann
Journal of Neurology  ·  04 Dec 2013  ·  doi:10.1007/s00415-013-7199-1
Subthalamic stimulation modulates self-estimation of patients with Parkinson’s disease and induces risk-seeking behaviour
Esther Florin, Désirée Müller, Johannes Pfeifer, Michael T. Barbe, Gereon R. Fink, Lars Timmermann
Brain  ·  25 Sep 2013  ·  doi:10.1093/brain/awt241
Discontinuities in slow finger movements in patients with Parkinson's disease
L.M. Bettray, C. Eggers, E.-L. Quatuor, E. Florin, C. Reck, A.K.M. Pauls, M.T. Barbe, G.R. Fink, L. Timmermann
Neuroscience Letters  ·  01 Aug 2013  ·  doi:10.1016/j.neulet.2013.02.068
Dopamine Replacement Modulates Oscillatory Coupling Between Premotor and Motor Cortical Areas in Parkinson's Disease
D. M. Herz, E. Florin, M. S. Christensen, C. Reck, M. T. Barbe, M. K. Tscheuschler, M. Tittgemeyer, H. R. Siebner, L. Timmermann
Cerebral Cortex  ·  02 Jun 2013  ·  doi:10.1093/cercor/bht140
Modulation of local field potential power of the subthalamic nucleus during isometric force generation in patients with Parkinson’s disease
E. Florin, H.S. Dafsari, C. Reck, M.T. Barbe, K.A.M. Pauls, M. Maarouf, V. Sturm, G.R. Fink, L. Timmermann
Neuroscience  ·  01 Jun 2013  ·  doi:10.1016/j.neuroscience.2013.02.043
Does increased gamma activity in patients suffering from Parkinson’s disease counteract the movement inhibiting beta activity?
E. Florin, R. Erasmi, C. Reck, M. Maarouf, A. Schnitzler, G.R. Fink, L. Timmermann
Neuroscience  ·  01 May 2013  ·  doi:10.1016/j.neuroscience.2013.01.051
Statistical pitfalls in the comparison of multivariate causality measures for effective causality
Esther Florin, Johannes Pfeifer
Computers in Biology and Medicine  ·  01 Feb 2013  ·  doi:10.1016/j.compbiomed.2012.11.009

2012

Clinical Outcome of Subthalamic Stimulation in Parkinson's Disease is Improved by Intraoperative Multiple Trajectories Microelectrode Recording
Mohammad Maarouf, Lars Wojtecki, Stefan Groiss, Esther Florin, Volker Sturm, Gereon Fink, Alfons Schnitzler, Lars Timmermann, Christiane Reck
Journal of Neurological Surgery Part A: Central European Neurosurgery  ·  05 Oct 2012  ·  doi:10.1055/s-0032-1326957
Essential tremor and tremor in Parkinson's disease are associated with distinct ‘tremor clusters’ in the ventral thalamus
David J. Pedrosa, Christiane Reck, Esther Florin, K. Amande M. Pauls, Mohammad Maarouf, …, Haidar Salimi Dafsari, Volker Sturm, Alfons Schnitzler, Gereon R. Fink, Lars Timmermann
Experimental Neurology  ·  01 Oct 2012  ·  doi:10.1016/j.expneurol.2012.07.002
Subtype-specific statistical causalities in parkinsonian tremor
E. Florin, M. Himmel, C. Reck, M. Maarouf, A. Schnitzler, V. Sturm, G.R. Fink, L. Timmermann
Neuroscience  ·  01 May 2012  ·  doi:10.1016/j.neuroscience.2012.02.045
Task-specific modulation of effective connectivity during two simple unimanual motor tasks: A 122-channel EEG study
Damian M. Herz, Mark S. Christensen, Christiane Reck, Esther Florin, Michael T. Barbe, Carsten Stahlhut, K. Amande M. Pauls, Marc Tittgemeyer, Hartwig R. Siebner, Lars Timmermann
NeuroImage  ·  01 Feb 2012  ·  doi:10.1016/j.neuroimage.2011.11.042
Parkinson's disease and pathological oscillatory activity: Is the beta band the bad guy? — New lessons learned from low-frequency deep brain stimulation
Lars Timmermann, Esther Florin
Experimental Neurology  ·  01 Jan 2012  ·  doi:10.1016/j.expneurol.2011.10.022

2011

Deep brain stimulation of the ventral intermediate nucleus in patients with essential tremor: Stimulation below intercommissural line is more efficient but equally effective as stimulation above
Michael T. Barbe, Lena Liebhart, Matthias Runge, Janina Deyng, Esther Florin, …, Niels Allert, Volker Sturm, Gereon R. Fink, Mohammad Maarouf, Lars Timmermann
Experimental Neurology  ·  01 Jul 2011  ·  doi:10.1016/j.expneurol.2011.04.005
Reliability of multivariate causality measures for neural data
Esther Florin, Joachim Gross, Johannes Pfeifer, Gereon R. Fink, Lars Timmermann
Journal of Neuroscience Methods  ·  01 Jun 2011  ·  doi:10.1016/j.jneumeth.2011.04.005

2010

Coherence analysis of local field potentials in the subthalamic nucleus: differences in parkinsonian rest and postural tremor
Christiane Reck, Matthias Himmel, Esther Florin, Mohammad Maarouf, Volker Sturm, Lars Wojtecki, Alfons Schnitzler, Gereon R. Fink, Lars Timmermann
European Journal of Neuroscience  ·  08 Sep 2010  ·  doi:10.1111/j.1460-9568.2010.07362.x
The effect of filtering on Granger causality based multivariate causality measures
Esther Florin, Joachim Gross, Johannes Pfeifer, Gereon R. Fink, Lars Timmermann
NeuroImage  ·  01 Apr 2010  ·  doi:10.1016/j.neuroimage.2009.12.050
Causality between local field potentials of the subthalamic nucleus and electromyograms of forearm muscles in Parkinson’s disease
Esther Florin, Joachim Gross, Christiane Reck, Mohammad Maarouf, Alfons Schnitzler, Volker Sturm, Gereon R. Fink, Lars Timmermann
European Journal of Neuroscience  ·  01 Feb 2010  ·  doi:10.1111/j.1460-9568.2010.07083.x

2009

Differential distribution of coherence between beta-band subthalamic oscillations and forearm muscles in Parkinson’s disease during isometric contraction
Christiane Reck, Esther Florin, Lars Wojtecki, Stefan Groiss, Jürgen Voges, Volker Sturm, Alfons Schnitzler, Lars Timmermann
Clinical Neurophysiology  ·  01 Aug 2009  ·  doi:10.1016/j.clinph.2009.05.018
Characterisation of tremor‐associated local field potentials in the subthalamic nucleus in Parkinson’s disease
Christiane Reck, Esther Florin, Lars Wojtecki, Holger Krause, Stefan Groiss, Jürgen Voges, Mohammad Maarouf, Volker Sturm, Alfons Schnitzler, Lars Timmermann
European Journal of Neuroscience  ·  01 Feb 2009  ·  doi:10.1111/j.1460-9568.2008.06597.x

2008

Ten Hertz thalamus stimulation increases tremor activity in the subthalamic nucleus in a patient with Parkinson’s disease
Esther Florin, Christiane Reck, Lothar Burghaus, Ralph Lehrke, Joachim Gross, Volker Sturm, Gereon R. Fink, Lars Timmermann
Clinical Neurophysiology  ·  01 Sep 2008  ·  doi:10.1016/j.clinph.2008.05.026

2007

Pathological cerebral oscillatory activity in Parkinson’s disease: a critical review on methods, data and hypotheses
Lars Timmermann, Esther Florin, Christiane Reck
Expert Review of Medical Devices  ·  01 Sep 2007  ·  doi:10.1586/17434440.4.5.651

2006

Method to rotate an endovascular device around the axis of a vessel using an external magnetic field
E. Florin, H. S. Rangwala, S. Rudin
Medical Physics  ·  26 Dec 2006  ·  doi:10.1118/1.2404641